RESEARCH | ucyoonjeepark

Research Projects

Theranostic Nanocomoplex: Drug Delivery Systems with Molecular Imaging

Microbubbles (2 um)

: Ultrasound Contrast Agents

Park et. al (2012) Langmuir

Philips

Theranostic Nanocomplex has the potential to simultaneously diagnose disease and act as therapeutics.

Zhe et al. Light-Activatable Theranostic Agents for Image-Monitored Controlled Drug Delivery, ACS Applied Materials and Interfaces, 2018.

On-demand drug release by external triggering mechanism can prolong drug delivery period and control drug dosage. (image from Chen et al 2015)

Nguyen et al. Multiple Exposure Drug Release From Stable Nanodroplets by High-Intensity Focused Ultrasound For a Potential Degenerative Disc Disease Treatment, Ultrasound in Medicine & Biology, 2018.

Long-Term Biodegradable Implants

Light-activated biodegradable implants for controlled release of drug using light-activated liposomal drugs.

He et al. Laser-Activated Drug Implant for Controlled Release to the Posterior Segment of the Eye, ACS Applied Biomaterials, 2021.

Light-activated biodegradable implants were activated to release drug by NIR laser in live rabbit eyes.

Molecular Level Interaction of Surfactant with Skin Surface

Depiction-of-how-surfactants-within-a-cl

Our lab is interested in the effect of surfactant on lubrication, hydration, and friction at the skin stratum corneum surface.

We hypothesize molecular interaction between surfactant and lipid or surface protein affects how we 'feel' the skin at different time periods of applying personal care products.

We investigate the effect using NMR and X-ray & neutron scattering with a skin stratum corneum mimic system that we created.

(Image adapted from Walters et al. 2012.)

Biomedical Colloid & Interface Lab

Principle Investigator: Yoonjee Park, PhD